Star Tribune file photo, 1964
Dr. William Worrall Mayo, an immigrant from England, establishes a medical practice in Rochester after being appointed as examining surgeon for the Union Army by President Abraham Lincoln. (Photo: Rochester, March 16, 1904.) Minnesota Historical Society/Mayo Clinic
Dr. Mayo’s oldest son, William J. Mayo (right), joins his medical practice.
Another son, Charles H. Mayo (left), comes aboard five years later. (Photo: 1908.)
Minnesota Historical Society/Mayo Clinic
The Mayo family doctors bring on specialists, establishing a team-based approach that remains a Mayo Clinic cornerstone today. Above: Dr. Charles H. Mayo, left, and Dr. William J. Mayo in Operating Room No. 1 in Saint Mary’s Hospital in Rochester in 1904. Minnesota Historical Society/Mayo Clinic
Dr. Henry Plummer, the Mayo family’s fourth partner, contributes to medical research and develops a unified “dossier” medical record and numeric registration system. The system was adapted for electronic records and is still in use. Minnesota Historical Society/Mayo Clinic
Officially adopts the name “Mayo Clinic” and opens a state-of-the-art medical building that includes the nation’s first large-scale telephone paging system.
(Photo: 1924. Building was demolished in 1986.)
Minnesota Historical Society/Mayo Clinic
Establishes the world’s first specialty training program for physicians, now known as the Mayo School of Graduate Medical Education. Above: Dr. Charles Mayo operates with observers looking on in 1913. Minnesota Historical Society/Mayo Clinic
The Mayo brothers and their wives donate the assets of their practice and most of their savings to establish Mayo Clinic as a not-for-profit organization. Above: Hattie Mayo, Dr. William J. Mayo with Dr. Charles H. Mayo and Edith Mayo, 1938. Star Tribune file photo
President Franklin D. Roosevelt visits Rochester and calls the Mayo brothers “teachers of America” in a radio broadcast. Above: Roosevelt with Charles, center, and William, right. Star Tribune file photo
Dr. Charles Mayo, 73, dies in Chicago of pneumonia on May 26, 1939. Dr. William Mayo, 78, dies in his sleep on July 28 in Rochester. Star Tribune file photos
Charles Lindbergh participates in top-secret research by the Mayo Clinic that leads to development of the G-suit and high-altitude oxygen masks used by WWII pilots. Above: Lindbergh, right, talks with World War II ace Maj. Thomas McGuire, Jr. on Dec. 4, 1945. Associated Press
For their discovery of cortisone, Mayo Clinic biochemist Edward Kendall, right, and Mayo rheumatologist Dr. Philip Hench, right, share the Nobel Prize in Physiology or Medicine along with Swiss chemist Tadeius Reinchstein. Star Tribune file photo
Mayo doctors perform the nation’s first clinical organ transplant in 1963 and the first FDA-approved hip replacement procedure in 1969. Star Tribune file photo
Mayo Medical School opens, the 110th medical school in the nation and second in Minnesota, after the University of Minnesota. Above: The Mitchell Student Center is a resource library for the Mayo Medical School. Provided by Mayo Clinic
In the 1980s, Mayo Clinic expands outside of Minnesota to open hospital campuses in Jacksonville, Fla., in 1986 (shown above), and in Scottsdale, Ariz., a year later. Provided by Mayo Clinic
Establishes Mayo Clinic Health System, which now owns hospitals and clinics in 71 cities in Minnesota, Iowa, Wisconsin and Georgia. Above: Emergency Health Clinic and helicopter landing pad in Cannon Falls. Provided by Mayo Clinic
The Gonda Building, 20 stories high and filled with art, opens in downtown Rochester as the hub for the medical campus. Glenn Stubbe • Star Tribune
Partners with the University of Minnesota, IBM and other industry leaders to establish U’s Rochester campus. Above: Chancellor Stephen Lehmkuhle rehearses the tassel switch with the first graduating class in 2013. David Joles • Star Tribune
Dr. John Noseworthy, a neurologist, becomes president and chief executive officer. David Joles • Star Tribune
Altru Health System in Grand Forks, N.D., becomes the first affiliate in the Mayo Clinic Care Network. The network now includes 31 health care organizations in 18 states,
Puerto Rico and Mexico.
Star Tribune graphic • Ray Grumney
Partners with UnitedHealth Group to create the nation’s largest health care data-mining project, known as Optum Labs. Above: John Penrod, computer system specialist with the Optum Labs medical database in Eden Prairie. Glenn Stubbe • Star Tribune
Minnesota Legislature approves $585 million in taxpayer funding to support Mayo's $5.6 billion, 20-year initiative to overhaul downtown Rochester and upgrade its medical campus. Renee Jones Schneider • Star Tribune